N,N-Dimethylformamide DMF

Product Overview

N,N-Dimethylformamide (also written NN dimethyl formamide, n n dimethyl formamide, N,N dimethylformamide) is a highly polar, water-miscible aprotic solvent with strong dissolving power and high thermal stability. It is commonly abbreviated as DMF, and is widely used as a process solvent, reaction medium, and extraction solvent in industrial and laboratory applications.
Colorless transparent liquid. It is a polar inert solvent. It can be mixed with water and most organic solvents except halogenated hydrocarbons.

Typical Specifications

Melting Point	-61 °C (lit.)
Alpha	0.94 º
Boiling Point	153 °C (lit.)
Density	0.944 g/mL (lit.)
Vapor Density	2.5 (vs air)
Vapor Pressure	2.7 mm Hg ( 20 °C)
Refractive Index	n20/D 1.430(lit.)
Fp	136 °F
Storage Temp.	Store at +5°C to +30°C.
Solubility	Water: miscible
PKA	-0.44±0.70(Predicted)
Form	Liquid
Color	APHA: ≤15
Appearance	Colorless liquid
PH	7 (200g/l, H2O, 20℃)
Odor	Faint, ammonia-like odor detectable at 100 ppm
Relative Polarity	0.386
Odor Threshold	1.8ppm
Explosive Limit	2.2-16%(V)
Water Solubility	Soluble

Key Applications

Pharmaceuticals and intermediates: used as a solvent and reaction medium in API and intermediate synthesis.
Polymer and resin processing: excellent solvent for polyurethane, acrylics, polyimides, and other high-performance materials.
Coatings and inks: supports resin dissolution, viscosity control, and formulation stability.
Chemical manufacturing: widely used in organics, extraction, and specialty synthesis.

Dimethylformamide is not only a widely used chemical raw material, but also an excellent solvent with a wide range of uses.

Dimethylformamide is a good solvent for a variety of polymers such as polyethylene, polyvinyl chloride, polyacrylonitrile, polyamide, etc., and can be used for wet spinning of synthetic fibers such as polyacrylonitrile fiber and the synthesis of polyurethane; It is used for plastic film making; it can also be used as a paint stripper for removing paint; it can also dissolve some low-solubility pigments, giving the pigments the characteristics of dyes.

Dimethylformamide is used for the extraction of aromatic hydrocarbons and for the separation and recovery of butadiene from the C4 fraction and the separation and recovery of isoprene from the C5 fraction. It can also be used as an effective reagent for the separation of non-hydrocarbon components from paraffin. 

It has good selectivity for the solubility of isophthalic acid and terephthalic acid: the solubility of isophthalic acid in dimethylformamide is greater than that of terephthalic acid, and solvent extraction or partial extraction in dimethylformamide is Crystallization can separate the two.

In the petrochemical industry, dimethylformamide can be used as a gas absorbent to separate and refine gases. In organic reactions, dimethylformamide is not only widely used as a reaction solvent, but also an important intermediate in organic synthesis.

In the pesticide industry, it can be used to produce pyrimidine; in the pharmaceutical industry, it can be used to synthesize iodine, doxycycline, cortisone, vitamin B6, iodine glycosides, fentanyl, pyrantel, N-formylsarcolyticin, anti- Oncosine, methoxychloride, benzene mustard, cyclohexylnitrosourea, furfururacil, hemostatic acid, befenmethane, megestrol, cholevitamin, chlorpheniramine, etc. Dimethylformamide has a catalytic effect in the reactions of hydrogenation, dehydrogenation, dehydration and dehydrohalogenation, lowering the reaction temperature and improving product purity.

Packaging, Grades & Supply

We supply DMF solvent in drums, IBCs, and bulk shipments for industrial buyers. COA and MSDS are available with each order. For procurement teams and distributors, please ask for DMF solvent price, dimethylformamide price, or DMF price based on your required grade and volume.

Why choose Greenchem International?

Stable export supply and strict quality control.
Flexible packaging and bulk logistics support.
Technical support for formulation and application selection.
Competitive commercial terms for long-term buyers.

Safety & Handling

DMF should be handled with appropriate PPE and good ventilation. Follow local regulations and the MSDS for storage, transport, and disposal.

Ordering & Inquiry

To buy N,N-Dimethylformamide (CAS 68-12-2) or request COA, MSDS and a competitive DMF price, please share your required grade, quantity and delivery country. We will reply with lead time and quotation.